OUR TECHNOLOGY

Industrial Chromatography, whether it is IEX (Ion EXchange), HIC (Hydrophobic InteraCtion), RPH (Reversed PHase), SEC (Size Exclusion) or AC (Affinity) Chromatography, in combination with membrane technology forms the core application of the Mosaic Systems Technology.

The key to our success is that we have proven to de-couple pressure drop (= through-put) from existing chromatography medium particle size. These medium particles are immobilised in a membrane-like structure ('mixed-matrix-membrane' structure) maintaining full chromatographic functionality.

We develop Module concepts to perform under a wide variety of process conditions, for high productivity, high resolution and low buffer consumption. Our start is the medium currently applied in your application. Through our patented mixed-matrix-membrane process we manufacture Modules for a variety of process conditions: pre-filtered feeds, direct adsorption from fermentation broth, combining filtration and chromatography.
  • Due to immobilisation of 5-10 um particles approximately 75% less medium necessary for certain productivity already in the capturing stage
  • Due to Mosaic Systems ModuleTM concept very robust, pre-validated, contained processing
  • Due to immobilisation protection of media from protein-agglomerates
  • Multiple cycles of adsorption can be performed without loss of efficiency
  • Due to smaller Module volume less buffer consumption
These combined factors make the Mosaic Systems Modules very cost-effective solution to industrial scale chromatography needs.


More on our technology:
  • Applications
  • Example application
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